Guanosine-5'-triphosphate disodium salt (GTP-Na2)

Application Areas

1. Product Overview

GTP-Na₂ (Guanosine 5'-Triphosphate Disodium Salt) is a purine nucleotide composed of guanosine and three phosphate groups. It is an essential molecule in energy metabolism, protein synthesis, and signal transduction, functioning both as an energy donor and as a regulator of numerous cellular processes. Due to its central biological role, GTP-Na₂ has wide applications in pharmaceuticals, diagnostics, research, and biotechnology.

 2. Main Application Fields

 1) Pharmaceutical Industry

 Drug intermediate: GTP-Na₂ is used as a raw material in the production of nucleotide-based drugs and intermediates.

 Therapeutic research: Plays a role in the study of diseases related to signal transduction, cancer, and neurological disorders, where GTP-binding proteins are involved.

 2) Scientific Research

 Protein synthesis: GTP is required in ribosomal translation during protein biosynthesis, serving as an energy source in elongation and initiation steps.

 Signal transduction: GTP acts as a substrate for GTP-binding proteins (G-proteins), which are critical regulators in cellular signaling pathways.

 Molecular biology: Extensively used in enzyme assays, nucleic acid synthesis, and biochemical pathway studies.

 Microtubule dynamics: GTP is essential for tubulin polymerization and cytoskeleton regulation, making it valuable in cell biology research.

 3) Diagnostics & Testing Reagents

 Enzymatic assays: GTP-Na₂ is applied in enzyme activity detection involving kinases, GTPases, and other GTP-dependent enzymes.

 Biochemical kits: Serves as a functional ingredient in in vitro diagnostic assays and molecular biology reagent kits.

 4) Biotechnology & Applied Fields

 In vitro transcription systems: GTP is a crucial substrate for RNA synthesis, widely used in cell-free transcription and mRNA production.

 Biopharmaceutical research: Used in the preparation of RNA-based therapeutics and vaccines, supporting nucleic acid biotechnology.